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RCMI Forum
Leigh Anne Shafer
Thursday, January 14, 2010
11:00 a.m. to 1 p.m.
MEB 301
The Role of the Natural Epidemiologic Cycle and Migration in Explaining the Course of the HIV Epidemic in Uganda: A Modelling Study

Leigh Anne Shafer, Ph.D.
Assistant Professor / Assistant Biostatistician
Department of Tropical Medicine, Medical Microbiology and Pharmacology
John A. Burns School of Medicine

People
Special Seminar
Ralph Etienne-Cummings, Ph.D.
Professor of Electrical and Computer Engineering
The Johns Hopkins University
Baltimore, Maryland
Biomorphic Circuits and Systems: Development and Applications of Silicon Models of the Nervous System

Tuesday October 6, 2009
12 noon to 1 p.m.
POST 127, UH Manoa Campus

Seminar Announcement
Seminar Description
Visit Schedule

Recent Grants Awarded
Peter Hoffmann
1R21AT004844-01A1 Hoffmann (PI) 8/01/2009-7/31/2011
NIH/NCCAM
Mechanisms by which Selenium Influences T Helper Cells During Immune Responses
The major goals of this project are to characterize mechanisms by which Se affects CD4+ T cell activation and identify specific selenoproteins that mediate the effects of Se on CD4+ T cells.

more information about Dr. Hoffmann's research
MM-1132-10/10 (Hernandez)
9/29/09-9/30/10
CDC
Evaluation of Genital Self-Sampling Methods for HPV Detection in Males
The major goal of this project is to evaluate self-sampling methods for HPV DNA detection in males.
Role: Principal Investigator

[Brenda Y. Hernandez, Ph.D., Associate Researcher, Cancer Research Center of Hawaii, has been supported by the RCMI Clinical and Translational Science Bridging Fund.]
Brenda Hernandez
Jun Panee
R21 AT005139-01 Panee (PI) 09/01/2009 - 8/31/2011
NIH/NCCAM
Exploratory Studies on the Anti-Breast Cancer Function of Bamboo Extract
This project aims to delineate the molecular mechanisms of the inhibitory effects of bamboo extract on the initiation of chemically-induced mammary tumors in lean rats. Cutting edge Magnetic Resonance Imaging (MRI) is used to quantitate the early growth of micro-tumors in the subjects.

more information about Dr. Panee's research
Research Highlights
The Neuroprotective Functions of Selenoprotein M and its Role in Cytosolic Calcium Regulation
Abstract

Figures

Reversal of West Nile Virus-induced Blood-brain Barrier Disruption and Tight Junction Proteins Degradation by Matrix Metalloproteinases Inhibitor

Abstract

Figure

Recent Publications
Bennett SN. Evolutionary Dynamics of Dengue Virus. In Frontiers in Dengue Virus Research, eds. K. A. Hanley and S.C. Weaver, 2010, p. 157-172.

Bennett SN, Drummond A, Kapan DD, Munoz J, Pybus O, Holmes EC, Gubler DJ. Epidemic dynamics revealed in dengue sequence evolution. Mol Biol Evol. 2009. Dec. 4 [Epub ahead of print]; doi: doi:10.1093/molbev/msp285. [PMID: 19965886].

Kang HJ, Arai S, Hope AG, Song JW, Cook JA, Yanagihara R. Genetic diversity and phylogeography of Seewis virus in the Eurasian common shrew in Finland and Hungary. Virol J. 2009; Nov 24;6(1):208. [Epub ahead of print]. [[PMID: 19930716]].

Reeves MA, Bellinger FP, Berry MJ. The Neuroprotective Functions of Selenoprotein M and its Role in Cytosolic Calcium Regulation. Antioxidants and Redox Signaling. 2009; Sep 21. [Epub ahead of print] [PMID: 19769485].

Verma S, Kumar M, Gurjav U, Lum S, Nerurkar, VR. Reversal of West Nile virus-induced blood–brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor. Virology. 2009. Nov 17. [Epub ahead of print] [PMID: 19922973].

Other
Stimulus Grant to Build Research Resource Network
Nine institutions of different sizes, geographical location, and culture have come together to build and implement a Federated National Informatics Network that will allow any investigator across America to discover research resources that are presently invisible. The team, named Networking Research Resources Across America includes Dartmouth College, Harvard University, Jackson State University, Morehouse School of Medicine, Montana State University, Oregon Health and Science University, University of Alaska Fairbanks, University of Hawaii Manoa, and University of Puerto Rico and truly spans America from coast to coast.

National Center for Research Resources Announcement

UH Press Release

12th RCMI International Symposium on Health Disparities
December 6-10, 2010
Renaissance Nashville Hotel - Nashville, TN

April 15, 2010 - Call for Abstracts & Registration
October 31, 2010 - Lodging Deadline
December 6, 2010 - Conference Begins

Research Outcomes Accelerating Discoveries for Medical Applications and Practice
The overall goal of the University of Hawaii RCMI Program is to significantly increase competitiveness for mainstream NIH funding by establishing a translational research interdisciplinary pipeline (TRIP) that leads to innovative medical applications and improved patient-care practices, particularly for diseases that disproportionately affect Asians and Pacific Islanders. [ more... ]
The University of Hawaii RCMI Program (G12RR003061) is funded by the Research Centers in Minority Institutions Program, an initiative of the National Center for Research Resources at the National Institutes of Health.